Whole blood assays
Whole Blood assays provides a physiological environment and are powerful tools to investigate immune responses. At BioMedha, we have on-site blood donor panel (HTA licenced establishment) and collect whole blood from consented healthy donors on the day of experiment setting up assays. Here, we summarize representative assay readouts developed at BioMedha.
CD11b activation
IL-1β assay
MMP-9 assay
Figure-1: CD11b+ activation in whole blood measured by Flowcytometry
Figure-2: IL-1β levels in whole blood measured by ELISA
Figure-3: MMP-9 activation in whole blood measured by AlphaLISA
CD45 toxicity
Phagocytosis
AchE inhibition
Figure-4: CD45+ cytotoxicity measured by Flowcytometry
Figure-5: Phagocytosis in whole blood measured by Flowcytometry
Figure-6: AchE inhibition in whole blood measured by ELISA
Phenotyping
Cytokine secretion
Figure-7: Immunophenotyping in whole blood by flowcytometry
Figure-8: Cytokine levels (basal) in whole blood measured by Luminex multiplexing
At BioMedha, we offer robust whole blood assays in multiple assay formats suitable for assessing compound effect, providing valuable insights into In vivo effects. Partner with us to accelerate your drug discovery portfolio.