Neutrophil assays
Targeting neutrophils is growing in immunology, immuno-oncology, and inflammation therapeutic areas. At BioMedha, we have developed robust In vitro assays using fresh neutrophils isolated from healthy donor whole blood. Suitable for assessing compound effect on neutrophil function.
CD11b activation
Figure-1: CD11b activation and inhibition in Neutrophils.
NETosis
Figure-2: PMA induced NETosis in Neutrophils using SytoxGreen.
GPCR function
Figure-3: Inhibition of C5a and IL-8 induced Ca flux.
Chemotaxis
Figure-4: Neutrophil Chemotaxis activation by IL-8 & C5a and inhibition of IL-8 & C5a induced chemotaxis.
At BioMedha, we have developed robust In vitro Neutrophils assays using freshly isolated neutrophils. We offer multiple assays to assess compound effect on neutrophil function. Partner with us to accelerate your drug discovery portfolio.